Bacteria belonging to the Clostridiales order help prevent a condition called “leaky gut syndrome,” which occurs when the cells lining the intestinal tract too easily allow pathogens and allergens to enter the bloodstream, often prompting excessive inflammation.
In addition, these bacteria are associated with a decreased risk for developing environmental and dietary allergies. Some evidence even suggests that if an allergic individual who is lacking in Clostridiales receives Clostridiales supplementation, the allergic reaction will decrease in severity or even disappear completely.
Clostridiales bacteria are not currently available in any commercial probiotics, because we do not yet have the technology to grow them in a laboratory. The only way to obtain them is through a fecal transplant.